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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK7 All Species: 14.55
Human Site: S678 Identified Species: 24.62
UniProt: Q13164 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13164 NP_002740.2 816 88386 S678 P P P G L P G S S T P G V L P
Chimpanzee Pan troglodytes XP_511332 494 55249 Q367 V Y P G A D R Q A L S L L G R
Rhesus Macaque Macaca mulatta XP_001099721 816 88521 S678 P P P G L P G S N T P G V L P
Dog Lupus familis XP_546651 731 80417 S604 A V L P Y F P S G P P P P E P
Cat Felis silvestris
Mouse Mus musculus Q9WVS8 806 87714 S668 P P S G L P G S G A P E V L P
Rat Rattus norvegicus P0C865 806 87808 S668 P P S G L P G S G A P E V L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518277 258 29416 Q130 G E M L A R R Q L F P G K N Y
Chicken Gallus gallus
Frog Xenopus laevis P26696 361 41238 K234 N R P I F P G K H Y L D Q L N
Zebra Danio Brachydanio rerio NP_001013469 862 94944 Q712 G E S V L P K Q P N K A Q V F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780133 1079 118303 S881 V L K G L R V S A T L M E S P
Poplar Tree Populus trichocarpa XP_002302599 372 42612 K245 R Q P L F P G K D Y V H Q L R
Maize Zea mays NP_001152745 397 44917 R270 R K P L F P G R D H V H Q L R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39024 376 42833 Y249 P L F P G K D Y V H Q L R L I
Baker's Yeast Sacchar. cerevisiae Q00772 484 55617 D357 M V I Q E V Q D F R L F V R Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.6 97.6 86.7 N.A. 92 92.1 N.A. 30.3 N.A. 24.1 47.3 N.A. N.A. N.A. N.A. 32.7
Protein Similarity: 100 54.6 98 87.9 N.A. 93.2 93.3 N.A. 31 N.A. 32.8 59.1 N.A. N.A. N.A. N.A. 46.7
P-Site Identity: 100 13.3 93.3 20 N.A. 73.3 73.3 N.A. 13.3 N.A. 26.6 13.3 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 26.6 100 20 N.A. 73.3 73.3 N.A. 13.3 N.A. 26.6 20 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 26.2 26.1 N.A. 25.7 28.8 N.A.
Protein Similarity: 35 35 N.A. 34.6 40.5 N.A.
P-Site Identity: 26.6 26.6 N.A. 13.3 6.6 N.A.
P-Site Similarity: 26.6 26.6 N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 15 0 0 0 15 15 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 8 15 0 0 8 0 0 0 % D
% Glu: 0 15 0 0 8 0 0 0 0 0 0 15 8 8 0 % E
% Phe: 0 0 8 0 22 8 0 0 8 8 0 8 0 0 8 % F
% Gly: 15 0 0 43 8 0 50 0 22 0 0 22 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 15 0 15 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 8 8 0 0 8 8 15 0 0 8 0 8 0 0 % K
% Leu: 0 15 8 22 43 0 0 0 8 8 22 15 8 58 0 % L
% Met: 8 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 8 8 0 0 0 8 8 % N
% Pro: 36 29 43 15 0 58 8 0 8 8 43 8 8 0 43 % P
% Gln: 0 8 0 8 0 0 8 22 0 0 8 0 29 0 8 % Q
% Arg: 15 8 0 0 0 15 15 8 0 8 0 0 8 8 22 % R
% Ser: 0 0 22 0 0 0 0 43 8 0 8 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 22 0 0 0 0 0 % T
% Val: 15 15 0 8 0 8 8 0 8 0 15 0 36 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 8 0 0 8 0 15 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _